Instrumental Data for Drug Analysis 1. [antikvár]

PREFACE Almost everyone engaged in the analysis of drug-related compounds, whether in the forensic, clinical, or university laboratory, has an accumulation of analytical data and thus has acquired a data base of sorts for the analysis of these compounds. Unfortunately, many of these compilations contain a number of unauthenticated "standards" acquired over a long period of time using various techniques and, perhaps, several generations of instrumentation. Some of the information contained in Instrumental Data for Drug Analysis is available in the literature; however, there is no single source that contains timely, quality data of this type presented in a large, easily usable format. This four volume set is the result of our desire to provide each laboratory in our own system with an authentic, up-to-date data base for the instrumental analysis of drugs. These volumes are neither a text nor a cookbook. They contain no analytical methods. They do provide the trained chemist with a single source of accurate instrumental data on twelve hundred drug-related compounds. We have included what we feel are the six currently most popular analytical techniques: ultraviolet (UV) spectrophotometry, infrared (IR) spectrophotometry, proton nuclear magnetic resonance (NMR) spectrometiy, mass spectrometry (MS), gas chromatography (GC), and high pressure liquid chromatography (HPLC). As we felt that the quality of data presented was of paramount importance in a reference source, we generated all of our data in our laboratory under uniform, reproducible conditions using state-of-the-art technology and verified chemical standards. In the second edition, we have included several new appendixes. A collection of supplemental infrared and nuclear magnetic resonance spectra comprises two of these appendixes. In these appendixes we have included many useful spectra not included in the main text. For diose users who do not have the assistance of computer search systems, we have compiled an infrared peak table index. Another new appendix is the molecular formula index. All of the NMR data has been revised using a 300 MHz FTNMR system. The MS data has been replotted in a more readable format. We hope that this book will be as helpful to all analytical chemists as it is to us. Terry Mills III J. Conrad Roberson